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["Name","Parameter","Units","Description"]
["CL",1,"L/h","Clearance"]
["V",10,"L","Volume of distribution"]
["ThalfAbs",1,"h","Absorption half-life"]
["Emax",-1,"unit","Maximum drug effect"]
["C50",1.5,"mg/L","Drug conc at 50% of Emax"]
["PCA0",1,"unit","Prothrombin Complex Activity at time=0"]
["ThalfPCA",24,"h","PCA half-life"]
[]
[null,"Dosing"]
["Dose",100,"mg","Drug dose at time=0"]
[]
[null,"Graph"]
["Tmax",168,"h","Time course maximum"]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
["Time course of prothrombin complex activity (PCA) described by PCA turnover with inhibition of synthesis; INR=International Normalized Ratio "]
["Holford N. Clinical pharmacokinetics and pharmacodynamics of warfarin. Understanding the dose-effect relationship. Clin Pharmacokinet. 1986;11(6):483-504."]

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